Effects of Ovariectomy and Dieting with Nano Calcium Phosphate on Bone Quality in White Rats Rattus norvegicus

Calcium supplements are widely used to prevent osteopenia and osteoporosis can be as a treatment along with other drugs. The effect of this supplement seen from the improved bone quality. focus in study was analyze quality femur based on mineral maturity degree crystallinity ovariectomized Rattus norvegicus where various nano calcium phosphate diets (1.0×; 1.5× 2.0× normal needs, respectively called A, B C diets) also given. In amount 40 white female rats age 12 weeks were 5 sham nurtured. group given euthanasia at 13 weeks, while treated 17 21 weeks. At 25 after ovariectomy, diet analysis performed when they 31 old. each harvest, proximal part collected characterized by using FTIR Spectroscopy. Rat shows trait for first time or 9 ovariectomy decreased 1.16 2.27 %, compared rat group. dietary conducted showed that fed A had not significant changes (p < 0.05) crystallinity, giving increase 15 diet. (6 weeks) faster than (15 weeks). Therefore, is recommended because it more efficient effective increases cost producing diet.
 HIGHLIGHTS
 
 Ovariectomy one treatments condition bones have osteoporosis. One parts often affected femur
 Bones restored diet
 Parameters analyzed regarding decline improvement include crystallinity. Assessment these parameters done Fourier Transform Infrared Spectroscopy
 GRAPHICAL ABSTRACT